Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.

All glucokinase gene mutations identified to date have been localized to exons that are common to the pancreatic and hepatic isoforms of the enzyme. While impaired insulin secretion has been observed in glucokinase-deficient subjects the consequences of this mutation on hepatic glucose metabolism re...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Velho, G, Petersen, K F, Perseghin, G, Hwang, J H, Rothman, D L, Pueyo, M E, Cline, G W, Froguel, P, Shulman, G I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507613/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118974
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