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Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.

All glucokinase gene mutations identified to date have been localized to exons that are common to the pancreatic and hepatic isoforms of the enzyme. While impaired insulin secretion has been observed in glucokinase-deficient subjects the consequences of this mutation on hepatic glucose metabolism re...

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Autors principals: Velho, G, Petersen, K F, Perseghin, G, Hwang, J H, Rothman, D L, Pueyo, M E, Cline, G W, Froguel, P, Shulman, G I
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC507613/
https://ncbi.nlm.nih.gov/pubmed/8878425
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