Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells.

Chronic lymphocytic leukemia (CLL) usually involves the expansion of a clone of CD5+ B cells synthesizing IgM antibodies. These B cells appear to be blocked at the antigen receptor-expressing stage of B cell differentiation and are thought not to undergo an isotype class switch to IgG or IgA product...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Fais, F, Sellars, B, Ghiotto, F, Yan, X J, Dono, M, Allen, S L, Budman, D, Dittmar, K, Kolitz, J, Lichtman, S M, Schulman, P, Schuster, M, Vinciguerra, V P, Rai, K, Stevenson, F K, Gregersen, P K, Ferrarini, M, Chiorazzi, N
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8833916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118961
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