Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells.

Chronic lymphocytic leukemia (CLL) usually involves the expansion of a clone of CD5+ B cells synthesizing IgM antibodies. These B cells appear to be blocked at the antigen receptor-expressing stage of B cell differentiation and are thought not to undergo an isotype class switch to IgG or IgA product...

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Detalhes bibliográficos
Main Authors: Fais, F, Sellars, B, Ghiotto, F, Yan, X J, Dono, M, Allen, S L, Budman, D, Dittmar, K, Kolitz, J, Lichtman, S M, Schulman, P, Schuster, M, Vinciguerra, V P, Rai, K, Stevenson, F K, Gregersen, P K, Ferrarini, M, Chiorazzi, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507600/
https://ncbi.nlm.nih.gov/pubmed/8833916
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