Peptides That Bind Specifically to an Antibody from a Chronic Lymphocytic Leukemia Clone Expressing Unmutated Immunoglobulin Variable Region Genes

Abstract Chronic lymphocytic leukemia (CLL) is a clonal disease of a subset of human B lymphocytes. Although the cause of the disease is unknown, its development and evolution appear to be promoted by signals delivered when B-cell receptors (BCRs) engage (auto)antigens. Here, using a peptide phage d...

Полное описание

Библиографические подробности

Главные авторы:	Yun Liu, Chelsea D Higgins, Cathie M Overstreet, Kanti R Rai, Nicholas Chiorazzi, Jonathan R Lai
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2013-08-01
Серии:	Molecular Medicine
Предметы:	Chronic Lymphocytic Leukemia Immunoglobulin Heavy Chain Diversity (IGHV) B-cell Receptor (BCRs) Phage Display Peptide Library Specific BCRs
Online-ссылка:	https://doi.org/10.2119/molmed.2013.00082
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