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Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat.

The mitogenic effect of activated coagulation factor X (factor Xa) was examined in cultured aortic smooth muscle cells (VSMC) from Wistar-Kyoto rats (WKY). Factor Xa stimulated DNA synthesis and cell growth in VSMC, not through the phospholipase C-protein kinase C pathway because increase of inosito...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Ko, F N, Yang, Y C, Huang, S C, Ou, J T
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8823316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118938
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