Human coagulation factor Va is a cofactor for the activation of protein C.
During blood clotting in vitro, protein C is converted in part to protein Ca, Protein Ca, in turn, inactivates factor Va. This is evidenced by the rapid inactivation of factor Va coagulant activity after clot formation which is associated with the cleavage of the Mr 110,000 peptide of factor Va. Whe...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1983
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6572921/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.6.1584 |
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