Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat.

The mitogenic effect of activated coagulation factor X (factor Xa) was examined in cultured aortic smooth muscle cells (VSMC) from Wistar-Kyoto rats (WKY). Factor Xa stimulated DNA synthesis and cell growth in VSMC, not through the phospholipase C-protein kinase C pathway because increase of inosito...

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Publicado en:	J Clin Invest
Principais autores:	Ko, F N, Yang, Y C, Huang, S C, Ou, J T
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8823316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118938
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