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Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases

Mammalian UDP-glucuronosyltransferases (UGTs) catalyze the transfer of glucuronic acid from UDP-glucuronic acid to various xenobiotics and endobiotics. Since UGTs comprise rate-limiting enzymes for metabolism of various compounds, co-administration of UGT-inhibiting drugs and genetic deficiency of U...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Fujiwara, Ryoichi, Yokoi, Tsuyoshi, Nakajima, Miki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075577/
https://ncbi.nlm.nih.gov/pubmed/27822186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00388
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