Modulation of gene expression in subjects at risk for colorectal cancer by the chemopreventive dithiolethione oltipraz.

Prolonged exposure to mutagenic substances is strongly associated with an individual's risk of developing colorectal cancer. Clinical investigation of oltipraz as a chemopreventive agent is supported by its induction of the expression of detoxication enzymes in various tissues, and its protecti...

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Main Authors: O'Dwyer, P J, Szarka, C E, Yao, K S, Halbherr, T C, Pfeiffer, G R, Green, F, Gallo, J M, Brennan, J, Frucht, H, Goosenberg, E B, Hamilton, T C, Litwin, S, Balshem, A M, Engstrom, P F, Clapper, M L
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507543/
https://ncbi.nlm.nih.gov/pubmed/8787684
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