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Hydrogen peroxide is a second messenger in phase 2 enzyme induction by cancer chemopreventive dithiolethiones
The ability of three dithiolethione cancer chemopreventives - oltipraz 1, anetholedithione (ADT) 2, 1,2-dithiole-3-thione (D3T) 3 and the major metabolite, 4, of 1 - to induce the cytoprotective enzyme NQO1 in hepa 1c1c7 cells and the inhibition of this induction by catalase is demonstrated. The abi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755628/ https://ncbi.nlm.nih.gov/pubmed/19785463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900110n |
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