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Dithiolethiones for Cancer Chemoprevention: Where Do We Stand?

Dithiolethiones are a well-known class of cancer chemopreventive agents, whose key mechanism of action involves activation of Nrf2 signaling and induction of Phase 2 enzymes. In the past, attention has been focused mainly on 4-methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione (oltipraz), which showed abil...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Yuesheng, Munday, Rex
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597301/
https://ncbi.nlm.nih.gov/pubmed/19001432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0625
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