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Deoxyribonuclease I is Essential for DNA Fragmentation Induced by Gamma Radiation in Mice

Gamma radiation is known to induce cell death in several organs. This damage is associated with endonuclease-mediated DNA fragmentation; however, the enzyme that produces the latter and is likely to cause cell death is unknown. To determine whether the most abundant cytotoxic endonuclease DNase I me...

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Dettagli Bibliografici
Pubblicato in:Radiat Res
Autori principali: Apostolov, Eugene O., Soultanova, Izoumroud, Savenka, Alena, Bagandov, Osman O., Yin, Xiaoyan, Stewart, Anna G., Walker, Richard B., Basnakian, Alexei G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075390/
https://ncbi.nlm.nih.gov/pubmed/19772469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1647.1
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