Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis

Carbamylated LDL (cLDL) is a potential atherogenic factor in chronic kidney disease (CKD). However, whether elevated plasma cLDL associates with atherosclerosis in vivo is unknown. Here, we induced CKD surgically in apolipoprotein E–deficient (ApoE(−/−)) mice fed a high-fat diet to promote the devel...

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Detalhes bibliográficos
Main Authors: Apostolov, Eugene O., Ray, Debarti, Savenka, Alena V., Shah, Sudhir V., Basnakian, Alexei G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014000/
https://ncbi.nlm.nih.gov/pubmed/20947625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040365
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