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Novel High-Throughput Deoxyribonuclease 1 Assay

Deoxyribonuclease I (DNase I), the most active and abundant apoptotic endonuclease in mammals, is known to mediate toxic, hypoxic, and radiation injuries to the cell. Neither inhibitors of DNase I nor high-throughput methods for screening of high-volume chemical libraries in search of DNase I inhibi...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Jang, Dae Song, Penthala, Narsimha R., Apostolov, Eugene O., Wang, Xiaoying, Fahmi, Tariq, Crooks, Peter A., Basnakian, Alexei G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564109/
https://ncbi.nlm.nih.gov/pubmed/25326282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057114555828
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