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Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.

The pathogenesis of systemic lupus erythematosus (SLE) is multifactorial and multigenetic. The apoptosis genes, fas and fas ligand (fasL), are candidate contributory genes in human SLE, as mutations of these genes result in autoimmunity in several murine models of this disease. In humans, fas mutati...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Wu, J, Wilson, J, He, J, Xiang, L, Schur, P H, Mountz, J D
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118892
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