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Amino Acid Sensing in Skeletal Muscle
Aging impairs skeletal muscle protein synthesis, leading to muscle weakness and atrophy. However, the underlying molecular mechanisms remain poorly understood. Here, we review evidence that mTORC1- and ATF4-mediated amino acid sensing pathways, triggered by impaired amino acid delivery to aged skele...
में बचाया:
| में प्रकाशित: | Trends Endocrinol Metab |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5075248/ https://ncbi.nlm.nih.gov/pubmed/27444066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2016.06.010 |
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