A DNA vaccine targeting TcdA and TcdB induces protective immunity against Clostridium difficile

BACKGROUND: Clostridium difficile-associated disease (CDAD) constitutes a great majority of hospital diarrhea cases in industrialized countries and is induced by two types of large toxin molecules: toxin A (TcdA) and toxin B (TcdB). Development of immunotherapeutic approaches, either active or passi...

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Vydáno v:BMC Infect Dis
Hlavní autoři: Zhang, Bao-Zhong, Cai, Jianpiao, Yu, Bin, Hua, Yanhong, Lau, Candy Choiyi, Kao, Richard Yi-Tsun Tsun, Sze, Kong-Hung, Yuen, Kwok-Yung, Huang, Jian-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075199/
https://ncbi.nlm.nih.gov/pubmed/27770789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1924-1
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