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Stringent Response Factors PPX1 and PPK2 Play an Important Role in Mycobacterium tuberculosis Metabolism, Biofilm Formation, and Sensitivity to Isoniazid In Vivo

Mycobacterium tuberculosis remains a global health threat largely due to the lengthy duration of curative antibiotic treatment, contributing to medical nonadherence and the emergence of drug resistance. This prolonged therapy is likely due to the presence of M. tuberculosis persisters, which exhibit...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Chuang, Yu-Min, Dutta, Noton K., Hung, Chien-Fu, Wu, T.-C., Rubin, Harvey, Karakousis, Petros C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075050/
https://ncbi.nlm.nih.gov/pubmed/27527086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01139-16
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