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Stringent Response Factors PPX1 and PPK2 Play an Important Role in Mycobacterium tuberculosis Metabolism, Biofilm Formation, and Sensitivity to Isoniazid In Vivo

Mycobacterium tuberculosis remains a global health threat largely due to the lengthy duration of curative antibiotic treatment, contributing to medical nonadherence and the emergence of drug resistance. This prolonged therapy is likely due to the presence of M. tuberculosis persisters, which exhibit...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Chuang, Yu-Min, Dutta, Noton K., Hung, Chien-Fu, Wu, T.-C., Rubin, Harvey, Karakousis, Petros C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075050/
https://ncbi.nlm.nih.gov/pubmed/27527086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01139-16
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