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Stringent Response Factors PPX1 and PPK2 Play an Important Role in Mycobacterium tuberculosis Metabolism, Biofilm Formation, and Sensitivity to Isoniazid In Vivo

Mycobacterium tuberculosis remains a global health threat largely due to the lengthy duration of curative antibiotic treatment, contributing to medical nonadherence and the emergence of drug resistance. This prolonged therapy is likely due to the presence of M. tuberculosis persisters, which exhibit...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Chuang, Yu-Min, Dutta, Noton K., Hung, Chien-Fu, Wu, T.-C., Rubin, Harvey, Karakousis, Petros C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075050/
https://ncbi.nlm.nih.gov/pubmed/27527086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01139-16
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