A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity. Implications for immune-mediated lung disease.

The A/Japan/57 influenza hemagglutinin (HA) was expressed in BALB/c mice under the transcriptional control of the surfactant protein C (SP-C) promoter, resulting in expression of HA in type II alveolar epithelial cells, as well as low level variable expression in other tissues, including the thymus...

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Detalhes bibliográficos
Main Authors: Enelow, R I, Stoler, M H, Srikiatkhachorn, A, Kerlakian, C, Agersborg, S, Whitsett, J A, Braciale, T J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507505/
https://ncbi.nlm.nih.gov/pubmed/8770862
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