Interference with Intraepithelial TNF-α Signaling Inhibits CD8(+) T-Cell-Mediated Lung Injury in Influenza Infection

CD8(+) T-cell-mediated pulmonary immunopathology in respiratory virus infection is mediated in large part by antigen-specific TNF-α expression by antiviral effector T cells, which results in epithelial chemokine expression and inflammatory infiltration of the lung. To further define the signaling ev...

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Detalhes bibliográficos
Main Authors: Srikiatkhachorn, Anon, Chintapalli, Jyothi, Liu, Jun, Jamaluddin, Mohammad, Harrod, Kevin S., Whitsett, Jeffrey A., Enelow, Richard I., Ramana, Chilakamarti V.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991178/
https://ncbi.nlm.nih.gov/pubmed/21142450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2010.0076
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