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Interference with Intraepithelial TNF-α Signaling Inhibits CD8(+) T-Cell-Mediated Lung Injury in Influenza Infection
CD8(+) T-cell-mediated pulmonary immunopathology in respiratory virus infection is mediated in large part by antigen-specific TNF-α expression by antiviral effector T cells, which results in epithelial chemokine expression and inflammatory infiltration of the lung. To further define the signaling ev...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Mary Ann Liebert, Inc.
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991178/ https://ncbi.nlm.nih.gov/pubmed/21142450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2010.0076 |
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