No tolerance to peripheral morphine analgesia in presence of opioid expression in inflamed synovia.
Pain treatment with centrally acting opiates is limited by tolerance. Tolerance is a decreasing effect of a drug with prolonged administration of that drug or of a related (e.g., endogenous) compound acting at the same receptor. This is often associated with a downregulation of receptors. In periphe...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118852 |
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