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Pairing Beyond the Seed Supports MicroRNA Targeting Specificity
To identify endogenous miRNA target sites, we isolated AGO-bound RNAs from Caenorhabditis elegans by individual-nucleotide resolution crosslinking-immunoprecipitation, which fortuitously also produced miRNA-target chimeric reads. Through the analysis of thousands of reproducible chimeras, pairing to...
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Publié dans: | Mol Cell |
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Auteurs principaux: | , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5074850/ https://ncbi.nlm.nih.gov/pubmed/27720646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.09.004 |
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