Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

Insulin resistance (IR) and impaired insulin secretion contribute to type 2 diabetes and cardiovascular disease. Both are associated with changes in the circulating metabolome, but causal directions have been difficult to disentangle. We combined untargeted plasma metabolomics by liquid chromatograp...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Nowak, Christoph, Salihovic, Samira, Ganna, Andrea, Brandmaier, Stefan, Tukiainen, Taru, Broeckling, Corey D., Magnusson, Patrik K., Prenni, Jessica E., Wang-Sattler, Rui, Peters, Annette, Strauch, Konstantin, Meitinger, Thomas, Giedraitis, Vilmantas, Ärnlöv, Johan, Berne, Christian, Gieger, Christian, Ripatti, Samuli, Lind, Lars, Pedersen, Nancy L., Sundström, Johan, Ingelsson, Erik, Fall, Tove
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074591/
https://ncbi.nlm.nih.gov/pubmed/27768686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006379
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi