Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance

Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood. Metabolic challenges like the oral glucose tolerance test (OGTT) can reveal pathogenic mechanisms. We aimed to discover associations of IR with metabolite trajectories during...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Nowak, Christoph, Hetty, Susanne, Salihovic, Samira, Castillejo-Lopez, Casimiro, Ganna, Andrea, Cook, Naomi L., Broeckling, Corey D., Prenni, Jessica E., Shen, Xia, Giedraitis, Vilmantas, Ärnlöv, Johan, Lind, Lars, Berne, Christian, Sundström, Johan, Fall, Tove, Ingelsson, Erik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989236/
https://ncbi.nlm.nih.gov/pubmed/29875472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26701-0
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