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Sequence-independent inhibition of in vitro vascular smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligodeoxynucleotides.

Phosphorothioate oligodeoxynucleotides (PS oligos) are antisense (sequence-specific) inhibitors of vascular smooth muscle cell (SMC) proliferation when targeted against different genes. Recently an aptameric G-quartet inhibitory effect of PS oligos has been demonstrated. To determine whether PS olig...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Wang, W, Chen, H J, Schwartz, A, Cannon, P J, Stein, C A, Rabbani, L E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507448/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118810
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