Sequence-independent inhibition of in vitro vascular smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligodeoxynucleotides.

Phosphorothioate oligodeoxynucleotides (PS oligos) are antisense (sequence-specific) inhibitors of vascular smooth muscle cell (SMC) proliferation when targeted against different genes. Recently an aptameric G-quartet inhibitory effect of PS oligos has been demonstrated. To determine whether PS olig...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Wang, W, Chen, H J, Schwartz, A, Cannon, P J, Stein, C A, Rabbani, L E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1996
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118810
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