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Mir-22-3p Inhibits Arterial Smooth Muscle Cell Proliferation and Migration and Neointimal Hyperplasia by Targeting HMGB1 in Arteriosclerosis Obliterans

Background: Aberrant vascular smooth muscle cell (VSMC) proliferation and migration contribute to the development of vascular pathologies, such as atherosclerosis and post-angioplasty restenosis. The aim of this study was to determine whether miR-22-3p plays a role in regulating human artery vascula...

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Principais autores: Shui-chuan Huang, Mian Wang, Wei-bin Wu, Rui Wang, Jin Cui, Wen Li, Zi-lun Li, Shen-ming Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
coleção:Cellular Physiology and Biochemistry
Assuntos:
Mirna-22-3p
Arteriosclerosis
Human arterial smooth muscle cell
Proliferation
Migration
Neointimal hyperplasia
HMGB1
Acesso em linha:http://www.karger.com/Article/FullText/480212
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