Pharmacokinetics of Bupropion and Its Pharmacologically Active Metabolites in Pregnancy

Bupropion sustained release is used to promote smoking cessation in males and nonpregnant females. However, its efficacy as a smoking cessation aid during pregnancy is not reported. The pregnancy-associated changes in maternal physiology may alter the pharmacokinetics and pharmacodynamics of bupropi...

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Veröffentlicht in:Drug Metab Dispos
Hauptverfasser: Fokina, Valentina M., Xu, Meixiang, Rytting, Erik, Abdel-Rahman, Sherif Z., West, Holly, Oncken, Cheryl, Clark, Shannon M., Ahmed, Mahmoud S., Hankins, Gary D.V., Nanovskaya, Tatiana N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074472/
https://ncbi.nlm.nih.gov/pubmed/27528039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.071530
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