Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

The deiodination of thyroid hormones in extrathyroidal tissues plays an important role in modulating thyroid hormone action. The type II deiodinase (DII) converts thyroxine to the active hormone 3,5,3'-triiodothyronine, and in the rat is expressed in the brain, pituitary gland, and brown adipose tis...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Croteau, W, Davey, J C, Galton, V A, St Germain, D L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118806
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