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Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

The deiodination of thyroid hormones in extrathyroidal tissues plays an important role in modulating thyroid hormone action. The type II deiodinase (DII) converts thyroxine to the active hormone 3,5,3'-triiodothyronine, and in the rat is expressed in the brain, pituitary gland, and brown adipose tis...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Principais autores: Croteau, W, Davey, J C, Galton, V A, St Germain, D L
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118806
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