Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

The deiodination of thyroid hormones in extrathyroidal tissues plays an important role in modulating thyroid hormone action. The type II deiodinase (DII) converts thyroxine to the active hormone 3,5,3'-triiodothyronine, and in the rat is expressed in the brain, pituitary gland, and brown adipose tis...

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Pubblicato in:	J Clin Invest
Autori principali:	Croteau, W, Davey, J C, Galton, V A, St Germain, D L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118806
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