Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation.

Excess vascular oxidative stress has been linked to impaired endothelium-dependent arterial relaxation in hypercholesterolemia. alpha-Tocopherol (AT) preserves endothelial function in hypercholesterolemia although the mechanism(s) for this protective effect is (are) not known. We examined the tissue...

Full description

Saved in:
Bibliographic Details
Published in:J Clin Invest
Main Authors: Keaney, J F, Guo, Y, Cunningham, D, Shwaery, G T, Xu, A, Vita, J A
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118804
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items