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Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation.

Excess vascular oxidative stress has been linked to impaired endothelium-dependent arterial relaxation in hypercholesterolemia. alpha-Tocopherol (AT) preserves endothelial function in hypercholesterolemia although the mechanism(s) for this protective effect is (are) not known. We examined the tissue...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Keaney, J F, Guo, Y, Cunningham, D, Shwaery, G T, Xu, A, Vita, J A
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1996
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118804
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