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Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors.

Receptor tyrosine kinases are important in cell signal transduction and proliferation. Abnormal expression of tyrosine kinases often leads to malignant transformation. C-met is a tyrosine kinase receptor and its ligand is hepatocyte growth factor (HGF). HGF/c-met plays diverse role in regulation of...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Liang, T J, Reid, A E, Xavier, R, Cardiff, R D, Wang, T C
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507382/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118744
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