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Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors.
Receptor tyrosine kinases are important in cell signal transduction and proliferation. Abnormal expression of tyrosine kinases often leads to malignant transformation. C-met is a tyrosine kinase receptor and its ligand is hepatocyte growth factor (HGF). HGF/c-met plays diverse role in regulation of...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1996
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675700/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118744 |
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