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TPR-MET oncogenic rearrangement: detection by polymerase chain reaction amplification of the transcript and expression in human tumor cell lines.

Activation of the MET protooncogene by a rearrangement involving the fusion of TPR and MET specific gene sequences has been observed in a human osteosarcoma cell line (HOS) treated in vitro with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). No information has been available about the possible occurre...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Soman, N R, Wogan, G N, Rhim, J S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53341/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2300559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.2.738
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