A novel methanol-free Pichia pastoris system for recombinant protein expression

BACKGROUND: As one of the most popular expression systems, recombinant protein expression in Pichia pastoris relies on the AOX1 promoter (P(AOX1)) which is strongly induced by methanol. However, the toxic and inflammatory nature of methanol restricts its application, especially in edible and medical...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Shen, Wei, Xue, Ying, Liu, Yiqi, Kong, Chuixing, Wang, Xiaolong, Huang, Mengmeng, Cai, Menghao, Zhou, Xiangshan, Zhang, Yuanxing, Zhou, Mian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073731/
https://ncbi.nlm.nih.gov/pubmed/27769297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0578-4
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