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A novel methanol-free Pichia pastoris system for recombinant protein expression
BACKGROUND: As one of the most popular expression systems, recombinant protein expression in Pichia pastoris relies on the AOX1 promoter (P(AOX1)) which is strongly induced by methanol. However, the toxic and inflammatory nature of methanol restricts its application, especially in edible and medical...
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| Veröffentlicht in: | Microb Cell Fact |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073731/ https://ncbi.nlm.nih.gov/pubmed/27769297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0578-4 |
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