Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124

Derepression of wild-type p53 by suppressing its negative inhibitor iASPP (Inhibitor of apoptosis-stimulating protein of p53) represents a potential therapeutic option for cervical cancer (CC). Here, we reported a novel functional significance of iASPP upregulation in cervical tumorigenesis: iASPP a...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Dong, Peixin, Xiong, Ying, Watari, Hidemichi, Hanley, Sharon JB, Konno, Yosuke, Ihira, Kei, Suzuki, Fumihiko, Yamada, Takahiro, Kudo, Masataka, Yue, Junming, Sakuragi, Noriaki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073231/
https://ncbi.nlm.nih.gov/pubmed/27765948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35480
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