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Both the anti- and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis

In the small intestine, epithelial cells are derived from stem cells in the crypts, migrate up the villus as they differentiate and are ultimately shed from the villus tips. This process of proliferation and shedding is tightly regulated to maintain the intestinal architecture and tissue homeostasis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Yaohong, George, Sudeep P., Roy, Swati, Pham, Eric, Esmaeilniakooshkghazi, Amin, Khurana, Seema
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073230/
https://ncbi.nlm.nih.gov/pubmed/27765954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35491
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