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By moonlighting in the nucleus, villin regulates epithelial plasticity

Villin is a tissue-specific, actin-binding protein involved in the assembly and maintenance of microvilli in polarized epithelial cells. Conversely, villin is also linked with the loss of epithelial polarity and gain of the mesenchymal phenotype in migrating, invasive cells. In this study, we descri...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Patnaik, Srinivas, George, Sudeep P., Pham, Eric, Roy, Swati, Singh, Kanchan, Mariadason, John M., Khurana, Seema
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751603/
https://ncbi.nlm.nih.gov/pubmed/26658611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0453
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