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Mapping General Anesthetic Sites in Heteromeric Gamma-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes

Intravenous general anesthetics including propofol, etomidate, alphaxalone, and barbiturates, produce important actions by enhancing gamma-aminobutyric acid type A (GABA-A) receptor activation. Here we review scientific studies that have located and mapped IV anesthetic sites using photoaffinity lab...

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Dettagli Bibliografici
Pubblicato in:Anesth Analg
Autori principali: Forman, Stuart A., Miller, Keith W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073028/
https://ncbi.nlm.nih.gov/pubmed/27167687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000001368
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