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Mapping General Anesthetic Sites in Heteromeric Gamma-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes

Intravenous general anesthetics including propofol, etomidate, alphaxalone, and barbiturates, produce important actions by enhancing gamma-aminobutyric acid type A (GABA-A) receptor activation. Here we review scientific studies that have located and mapped IV anesthetic sites using photoaffinity lab...

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Bibliographic Details
Published in:Anesth Analg
Main Authors: Forman, Stuart A., Miller, Keith W.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073028/
https://ncbi.nlm.nih.gov/pubmed/27167687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000001368
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