Cytoplasmic localization of FAC is essential for the correction of a prerepair defect in Fanconi anemia group C cells.
Mutations in the gene defective in Fanconi anemia complementation group C, FAC, are responsible for a subset of Fanconi anemia, a group of autosomal recessive disorders characterized by chromosomal instability, hypersensitivity to cross-linking agents, and cancer susceptibility. Although abnormaliti...
Kaydedildi:
| Yayımlandı: | J Clin Invest |
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| Yazar: | |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621788/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118635 |
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