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Induction of Fanconi anemia cellular phenotype in human 293 cells by overexpression of a mutant FAC allele.
The polypeptide encoded by the Fanconi anemia (FA) complementation group C gene, FAC, binds to a group of cytoplasmic proteins in vitro and may form a multimeric complex. A known mutant allele of FAC resulting from the substitution of Pro for Leu at codon 554 fails to correct the sensitivity of FA g...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507141/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8613549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118519 |
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