Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses

IFI16 (gamma-interferon-inducible protein 16), a predominantly nuclear protein involved in transcriptional regulation, also functions as an innate immune response DNA sensor and induces the IL-1β and antiviral type-1 interferon-β (IFN-β) cytokines. We have shown that IFI16, in association with BRCA1...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Iqbal, Jawed, Ansari, Mairaj Ahmed, Kumar, Binod, Dutta, Dipanjan, Roy, Arunava, Chikoti, Leela, Pisano, Gina, Dutta, Sujoy, Vahedi, Shahrooz, Veettil, Mohanan Valiya, Chandran, Bala
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072618/
https://ncbi.nlm.nih.gov/pubmed/27764250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005967
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