Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses

The IL-1β and type I interferon-β (IFN-β) molecules are important inflammatory cytokines elicited by the eukaryotic host as innate immune responses against invading pathogens and danger signals. Recently, a predominantly nuclear gamma-interferon-inducible protein 16 (IFI16) involved in transcription...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ansari, Mairaj Ahmed, Dutta, Sujoy, Veettil, Mohanan Valiya, Dutta, Dipanjan, Iqbal, Jawed, Kumar, Binod, Roy, Arunava, Chikoti, Leela, Singh, Vivek Vikram, Chandran, Bala
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489722/
https://ncbi.nlm.nih.gov/pubmed/26134128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005019
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