ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi’s Sarcoma-Associated Herpesvirus

Kaposi’s sarcoma-associated herpesvirus (KSHV) binding to the endothelial cell surface heparan sulfate is followed by sequential interactions with α3β1, αVβ3 and αVβ5 integrins and Ephrin A2 receptor tyrosine kinase (EphA2R). These interactions activate host cell pre-existing FAK, Src, PI3-K and Rho...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kumar, Binod, Dutta, Dipanjan, Iqbal, Jawed, Ansari, Mairaj Ahmed, Roy, Arunava, Chikoti, Leela, Pisano, Gina, Veettil, Mohanan Valiya, Chandran, Bala
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072609/
https://ncbi.nlm.nih.gov/pubmed/27764233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005960
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