Loading...

Genomic Disruption of VEGF-A Expression in Human Retinal Pigment Epithelial Cells Using CRISPR-Cas9 Endonuclease

PURPOSE: To employ type II clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 endonuclease to suppress ocular angiogenesis by genomic disruption of VEGF-A in human RPE cells. METHODS: CRISPR sequences targeting exon 1 of human VEGF-A were computationally identified based on pred...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Yiu, Glenn, Tieu, Eric, Nguyen, Anthony T., Wong, Brittany, Smit-McBride, Zeljka
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072539/
https://ncbi.nlm.nih.gov/pubmed/27768202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20296
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!