Hyperalphalipoproteinemia in human lecithin cholesterol acyltransferase transgenic rabbits. In vivo apolipoprotein A-I catabolism is delayed in a gene dose-dependent manner.

Lecithin cholesterol acyltransferase (LCAT) is an enzyme involved in the intravascular metabolism of high density lipoproteins (HDLs). Overexpression of human LCAT (hLCAT) in transgenic rabbits leads to gene dose-dependent increases of total and HDL cholesterol concentrations. To elucidate the mecha...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Brousseau, M E, Santamarina-Fojo, S, Zech, L A, Bérard, A M, Vaisman, B L, Meyn, S M, Powell, D, Brewer, H B, Hoeg, J M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507252/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118614
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