Hyperalphalipoproteinemia in human lecithin cholesterol acyltransferase transgenic rabbits. In vivo apolipoprotein A-I catabolism is delayed in a gene dose-dependent manner.

Lecithin cholesterol acyltransferase (LCAT) is an enzyme involved in the intravascular metabolism of high density lipoproteins (HDLs). Overexpression of human LCAT (hLCAT) in transgenic rabbits leads to gene dose-dependent increases of total and HDL cholesterol concentrations. To elucidate the mecha...

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Main Authors: Brousseau, M E, Santamarina-Fojo, S, Zech, L A, Bérard, A M, Vaisman, B L, Meyn, S M, Powell, D, Brewer, H B, Hoeg, J M
Formato: Artigo
Idioma:Inglês
Publicado: 1996
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC507252/
https://ncbi.nlm.nih.gov/pubmed/8621767
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